Ziapam 5mg/ml Solution Injection (CD Sch 4)
TVM UK ANIMAL HEALTH LTD T/A DOMES PHARMA
Ziapam 5mg/ml Solution Injection (CD Sch 4) from TVM UK ANIMAL HEALTH LTD T/A DOMES PHARMA is supplied as a solution for injection.
LEGAL CLASSIFICATION:POM-V
THIS IS A SCHEDULE 4 CONTROLLED DRUG AND THEREFORE REQUIRES THE ORIGINAL PRESCRIPTION POSTING TO US.
To expedite screening and dispensing, please email a scan/photo of the signed prescription to mail@vets4u.uk first, then post the original signed paper prescription to our address. UK Controlled Drug regulations require us to hold the original on file.
We also require information about you and your Pet for us to be able to dispense your Pets medicine, please provide us with all your up to date information in the Question boxes below.
A link to the Medicine SPC on the VMD Product database can be found here: VMD Product Database
UK Public Assessment Report: UKPAR (PDF)
Post-Authorisation Assessment Report: PAAR (PDF)
Active Ingredient(s)
Diazepam
Pack & Presentation
Form: Solution for injection · Pack size: 6X2ML
Suitable Species
Cats, Dogs
Regulatory Information
- Legal category: POM-V
- Marketing authorisation holder: Laboratoire TVM 57 rue des Bardines 63370 Lempdes France Further information Diazepam is a central nervous system depressant which may potentiate the action of other central nervous system depressants as barbiturates, tranquilizers, narcotics, antidepressants. Diazepam may increase the action of digoxin. Cimetidine, erythromycin, azole substances (such as itraconazole or ketoconazole) valproic acid and propanol may slow the metabolism of diazepam. The dose of diazepam may need to be decreased to avoid excessive sedation. Dexamethasone may decrease the action of diazepam. The concomitant use with hepatotoxic dosages of other substances should be avoided. When administered alone, diazepam overdose may cause significant central nervous system depression (confusion, decreased reflexes, coma, etc). Supportive treatment should be given (cardio-respiratory stimulation, oxygen). Hypotension and respiratory and cardiac depression are rare events. Diazepam is a benzodiazepine derivative thought to depress the sub-cortical levels of the central nervous system (primarily limbic, thalamic and hypothalamic) to produce anxiolytic, sedative, musculoskeletal relaxant and anticonvulsant effects. The exact mechanism of action has not been defined. Diazepam is highly lipid soluble and is widely distributed throughout the body. It readily crosses the blood-brain barrier and is highly bound to plasma proteins. It is metabolised in the liver to produce several pharmacologically active metabolites (major metabolite in dogs is N-desmethyl-diazepam), which are conjugated with glucuronide and eliminated primarily in the urine.
- MA number: Vm 35079/4002
Important Notice
The information on this page is provided for general guidance only and does not replace the advice of a qualified veterinary surgeon. Always follow the directions provided on the product packaging and by your veterinary practice. If your animal's condition does not improve, worsens, or any side effects occur, contact your veterinary surgeon immediately.
