Senvelgo Product Information
Questions
What conditions does Senvelgo treat?
It can be prescribed for the treatment of diabetes mellitus in cats
How does Senvelgo work?
It contains Velagliflozin whichis a selective inhibitor of the sodium-glucose co-transporter 2 (SGLT 2) which is predominantly expressed in the kidney. Velagliflozin also has a minor inhibitory effect on the SGLT-1 which is predominantly expressed in the small intestine, but also expressed at a lower level in the kidney. SGLT 2 is the primary transporter for the reabsorption of glucose from the urine. The inhibition of the SGLT 2 leads to glucose elimination in the urine and results in a decrease in elevated blood glucose levels in diabetic patients.
How should I administer Senvelgo to my pet?
It is an oral solution to be given by mouth following your vet’s directions on the label provided.
Precautions when administering the medicine
Accidental exposure to the product may cause increased urination, and symptoms of low blood pressure or low blood sugar, such as dizziness.
Take care to avoid children accessing an unattended filled syringe.
Do not leave the syringe unattended. Ensure that the food bowl is washed after the cat has eaten food which was mixed with the product.
If skin contact occurs, avoid hand-to-mouth contact, and wash hands immediately.
If symptoms occur, seek medical advice.
The product may cause slight irritation to the eyes.
Avoid contact with the eyes.
If contact with the eyes occurs, rinse immediately with water, and seek medical advice if symptoms persist.
The product includes propylene glycol, which may cause hypersensitivity reactions. People with known hypersensitivity to this substance should avoid contact with the product.As no data are available to conclude that exposure to velagliflozin presents a risk to pregnant and/or breastfeeding women, they should consider wearing gloves in addition to standard hygiene practices.
What is the correct dosage of Senvelgo for my animal's weight and species?
The correct dose for your animal is as prescribed by your vet. Your vet will follow the data sheet for the medication prescribed and for some medications will adjust this taking into consideration your animal's medical history.
How long should I continue with Senvelgo for?
You should continue for the length of time your vet prescribed the medication for. Please read the label your vet has attached to the medication. If you suspect that your pet may be having an adverse reaction to a medication, please contact your vet for advice on continuing the medication.
What should I do if I miss a dose of Senvelgo?
If you miss a dose of medication, please contact your vet for advice on when to give the next dose.
Where can I buy Senvelgo?
You can purchase Senvelgo cheaper than from your Vet Practice from www.vets4u.uk. To contact vets4u.uk, call us on +44 116 218 4244 between 09:30am and 4:30pm Monday to Friday, chat to us directly or email us at mail@vets4u.uk.
Does Senvelgo need a prescription?
Yes, as it is classified as a POM-V.
How can I buy Senvelgo from Vets4u?
You can buy Senvelgo via our website via a valid prescription by adding to the basket on our website www.vets4u.uk.
Manufacturer’s Link to Senvelgo
NOAH Compendium Datasheet Link to Senvelgo
What are the side-effects of Senvelgo?
Very common (>1 per 10 animals treated):
Around half of cats can be expected to display loose stool/diarrhoea during treatment. In the majority of incidences, loose stool/diarrhoea last for seven days or less and usually resolves without specific treatment.
About 25% of cats can experience loose stool/diarrhoea lasting longer than 28 days. In case diarrhoea persists, alternative treatment for diabetes mellitus should be considered on a case-by-case basis.
Polydipsia/polyuria: resolves without additional treatment; may occur as part of the underlying disease or may be enhanced due to the osmotic effect of velagliflozin.
Weight loss: may occur as part of the underlying disease. An initial weight loss may occur due to the glucosuric effect of velaglifilozin.
Mild dehydration.
Common( 1-10 per 100 animals treated):
Diabetic ketoacidosis (DKA): may be euglycaemic. Stop treatment and initiate insulin therapyDiabetic ketonuria: Urinary tract infection including cystitis caused by infection: may occur as part of the underlying disease. The glucosuric effect of velagliflozin may contribute to urinary tract infection. Standard cystitis/urinary tract infection therapy should be initiated.
Hypersalivation: usually at initial administrations only, occurs immediately following dosing and resolves quickly, without the need for treatment.
Can Senvelgo cause hypoglycaemia?
Yes it could do.
Is Senvelgo suitable for cats and dogs?
It is licensed for use in cats only.
Senvelgo or insulin, which is better?
This is a discussion you need to have with your vet who knows your cat’s medical history. Each may work adequately for your pet.
Answers Compiled by our RCVS Registered Veterinary Surgeon.