Onsior Product Information

Onsior Questions

What conditions does Onsior treat?

For the treatment of pain and inflammation associated with chronic osteoarthritis in dogs.

For the treatment of pain and inflammation associated with soft tissue surgery in dogs.

For the treatment of pain and inflammation associated with acute or chronic musculo-skeletal disorders in cats.

For the reduction of moderate pain and inflammation associated with orthopaedic surgery in cats.

How does Onsior work?

It contains Robenacoxib, which is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. It is a potent and selective inhibitor of the cyclooxygenase 2 enzyme (COX-2).

The cyclooxygenase enzyme (COX) is present in two forms. COX-1 is the constitutive form of the enzyme and has protective functions, e.g. in the gastrointestinal tract and kidneys. COX-2 is the inducible form of the enzyme and is responsible for the production of mediators including PGE2 which induce pain, inflammation or fever.

How should I administer Onsior to my pet?

It is given by mouth as a tablet so orally.

Wash hands after use of the veterinary medicinal product.

In small children, accidental ingestion increases the risk for NSAID adverse effects. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

In pregnant women, particularly near to term pregnant women, prolonged dermal exposure increases the risk for premature closure of the ductus arteriosus in the foetus.

What is the correct dosage of Onsior for my animal's weight and species?

The correct dose for your animal is as prescribed by your vet. Your vet will follow the data sheet for the medication prescribed and for some medications will adjust this taking into consideration your animal's medical history.

How long should I continue with Onsior for?

You should continue for the length of time your vet prescribed the medication for. Please read the label your vet has attached to the medication. If you suspect that your pet may be having an adverse reaction to a medication, please contact your vet for advice on continuing the medication.

What should I do if I miss a dose of Onsior?

If you miss a dose of medication, please contact your vet for advice on when to give the next dose.

Where can I buy Onsior?

You can purchase Onsior cheaper than from your Vet Practice from www.vets4u.uk. To contact vets4u.uk, call us on +44 116 218 4244 between 09:30am and 4:30pm Monday to Friday, chat to us directly or email us at mail@vets4u.uk

Does Onsior need a prescription?

Yes, as it is classified as a POM-V.

How can I buy Onsior from Vets4u?

You can buy Onsior via our website via a valid prescription by adding to the basket on our website www.vets4u.uk.

Manufacturer’s Link to Onsior

Elanco - Onsior

NOAH Compendium Datasheet Link to Onsior

Onsior Datasheet

What are the side-effects of Onsior?

In cats:

Common (1 to 10 animals / 100 animals treated): Diarrhoea1, Vomiting1

Very rare (< 1 animal / 10,000 animals treated, including isolated reports) 

Elevated renal parameters (creatinine, BUN, and SDMA)2 Renal insufficiency2 Lethargy

1 Mild and transient.

2 More commonly in older cats and with concomitant use of anaesthetic or sedative agents

In dogs:

Very common (>1 animal / 10 animals treated): Digestive tract disorder1, Diarrhoea, Vomiting

Common (1 to 10 animals / 100 animals treated): Elevated liver enzymes2 Decreased appetite

Uncommon (1 to 10 animals / 1,000 animals treated): Blood in the faeces

Very rare (< 1 animal / 10,000 animals treated, including isolated reports): Lethargy1Most cases were mild and recovered after treatment.

In dogs treated up to 2 weeks, there were no increases in liver enzyme activities observed. However, with long-term treatment, increases in liver enzyme activities were reported. In most cases there were no clinical signs and the liver enzyme activities either stabilised or decreased with continued treatment. Increases in liver enzyme activities associated with clinical signs of anorexia, apathy or vomiting were uncommon.

How safe is Onsior for dogs

It is licensed for use in dogs for treatment of pain and inflammation associated with chronic arthritis and after surgical operations so long as they are over 2.5 kg in weight and more than 3 months of age.

Commonly gastrointestinal adverse events are reported such as vomiting or soft faeces, reduced appetite or diarrhoea. With long term treatment liver enzymes increasing is common which may be associated with anorexia, lethargy and vomiting, but uncommonly.

Commonly is more than 1 but less than 10 animals in 100.

Uncommon is more than 1 but less than 10 in 1000 animals.

It should not be used in pregnancy or lactation.

Can Onsior be used long term?

It can if your vet prescribes it. Liver enzymes need to be monitored at the start of treatment and after 2, 4 and 8 weeks and thereafter, every 3-6 months.

Can Onsior be crushed?

It should not be given with food, it is more effective given without food or at least 30 minutes before or after a meal.

Does Onsior make cats sleepy?

Rarely it will lead to lethargy. Rarely is more than 1 but less than 10 animals in 1000.

How long does it take for Onsior to work?

For chronic musculoskeletal problems, a response is usually seen within 3-6 weeks.
It works quickly, within half an hour, when used prior to surgery for pain relief and daily afterwards.

How long is treatment with Onsior?

It needs to be given daily for as long as your vet prescribes it.

Can Onsior and Metacam be taken together?

No.

Can Onsior for cats be crushed?

No, they should be given in cats either without food or with a small amount of food.

Is Onsior the same as Metacam?

They are similar in that they are non-steroidal anti-inflammatory drugs but have different content.

Can Onsior and Gabapentin be taken together?

If your vet prescribes them, then yes.

Is Onsior a painkiller?

Yes.

Will Onsior make my dog sleepy?

Uncommonly lethargy will be an adverse reaction.

Uncommonly is more than 1 but less than 10 animals in 1000.

Answers Compiled by our RCVS Registered Veterinary Surgeon.