Galliprant Product Information

Galliprant Questions

What conditions does Galliprant treat?
It is for the treatment of pain associated with mild to moderate osteoarthritis in dogs.

How does Galliprant work?
It contains Grapiprant which is a non-steroidal, non-cyclooxygenase inhibiting anti-inflammatory drug in the piprant class. Grapiprant is a selective antagonist of the EP4 receptor, a key prostaglandin E2 receptor that predominantly mediates prostaglandin E2‐elicited nociception. The specific effects of the binding of prostaglandin E2 to the EP4 receptor include vasodilation, increased vascular permeability, angiogenesis and production of pro‐inflammatory mediators. The EP4 receptor is important in mediating pain and inflammation as it is the primary mediator of the prostaglandin E2-elicited sensitization of sensory neurons and prostaglandin E2-elicited inflammation.

How should I administer Galliprant to my pet?
It is a tablet so should be given orally, by mouth. Wash hands after handling of the veterinary medicinal product.

In case of accidental ingestion by children, mild and reversible gastrointestinal signs and nausea may be observed. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

What is the correct dosage of Galliprant for my animal's weight and species?

The correct dose for your animal is as prescribed by your vet. Your vet will follow the data sheet for the medication prescribed and for some medications will adjust this taking into consideration your animal's medical history.

How long should I continue with Galliprant for?

You should continue for the length of time your vet prescribed the medication for. Please read the label your vet has attached to the medication. If you suspect that your pet may be having an adverse reaction to a medication, please contact your vet for advice on continuing the medication.

What should I do if I miss a dose of Galliprant?

If you miss a dose of medication, please contact your vet for advice on when to give the next dose.

Where can I buy Galliprant?

You can purchase Galliprant cheaper than from your Vet Practice from www.vets4u.uk. To contact vets4u.uk, call us on +44 116 218 4244 between 09:30am and 4:30pm Monday to Friday, chat to us directly or email us at mail@vets4u.uk.

Does Galliprant need a prescription?

Yes, as it is classified as a POM-V.

How can I buy Galliprant from Vets4u?

You can buy Galliprant via our website via a valid prescription by adding to the basket on our website www.vets4u.uk.

Manufacturer’s Link to Galliprant

Galliprant

NOAH Compendium Datasheet Link to Galliprant

Galliprant Datasheet

What are the side-effects of Galliprant?

Very common (>1 animal/10 treated)-vomiting.

Common (1-10 animals per 100 treated –loose stool, diarrhoea, inappetence.

Very Rare (<1 animal per 10,000 treated) - Haematemesis, Haemorrhagic diarrhoea.

Pancreatitis,Elevated blood urea nitrogen (BUN), Elevated creatinine, Elevated liver enzymes, Hypoalbuminaemia1, Hypoproteinaemia1.

Does Galliprant cause panting?

It is not listed on the product datasheet as a side effect. If your dog is panting then please contact your vet for advice.

Does Galliprant affect the liver?

Rarely, it can lead to liver enzymes being raised on a blood test. It should be used with caution in animals with pre-existing liver disease.

Does Galliprant make dogs sleepy?

Sleepiness is not listed as a side effect. If your dog’s behaviour changes, then please contact your vet for advice.

Does Galliprant need to be given with food?

No, it should be given on an empty stomach an hour or more before the next meal.

How long does Galliprant last?

It should be given once daily. It is mostly excreted from the body within 48-72 hours, it’s half-life being 4.6 - 5.67 hours. 

How long does it take for Galliprant to work?

It is rapidly absorbed and reaches its maximum concentration in the blood within an hour, so will start to have some effects from then but it may take seven days for you to notice a difference in your dog.

The success rate after 28 days has been recorded at 51.3%. If there is no improvement after 2 weeks, then it should be discussed with your vet whether to discontinue use and try other options.

Is Galliprant a painkiller?

Yes, for mild to moderate arthritis.

What is Galliprant?

It contains a drug called Grapiprant and is an anti-inflammatory painkiller.

Why is Galliprant so expensive?

Every supplier will have their own price so you can compare prices, your vet’s price and online pharmacy prices. Your vet will have a charge for giving you a written prescription to use at an online pharmacy.

Does Galliprant make dogs thirsty?

It is not listed as a side effect, if your pet is thirstier, then please contact your vet.

Can a dog overdose on Galliprant?
If you accidentally give more than the prescribed dose, then yes this would be an overdose. Symptoms may include soft formed or mucous containing faeces, occasionally bloody, and vomiting if the dose is more than 2.5 x the recommended dose.

It does not affect the liver or kidneys at 15 x the recommended dose.

Can dogs take Gabapentin and Galliprant together?

Ask your vet, as this will depend on your individual pet’s general health.

Does Galliprant cause diarrhoea in dogs?

Yes, it can do so please inform your vet if this occurs

Is Galliprant and Gabapentin the same?

No, they are different drugs.

Is Galliprant better than Metacam?

They are different, either may work better in your individual dog.

Are Galliprant and Carprofen the same?

No, they contain different drugs.

Can Galliprant make dogs worse?

No.

Answers Compiled by our RCVS Registered Veterinary Surgeon.