Milbemax Product Information

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Milbemax Questions

What conditions does Milbemax treat?
For dogs, cats and kittens.

For dogs it treats:

For dogs with, or at risk from mixed infections of cestodes, gastrointestinal nematodes, eyeworm, lungworms and/or heartworm.

This veterinary medicinal product is only indicated when use against cestodes and nematodes or prevention of heartworm disease/angiostrongylosis is indicated at the same time.

Cestodes

Treatment of tapeworms: Dipylidium caninum, Taenia spp., Echinococcus spp., Mesocestoides spp.

Gastrointestinal nematodes

Treatment of:

Hookworm: Ancylostoma caninum,

Roundworms: Toxocara canis, Toxascaris leonina,

Whipworm: Trichuris vulpis.

Eyeworm

Treatment of Thelazia callipaeda (see specific treatment schedule under section “Administration routes and dosage”).

Lungworms

Treatment of:

Angiostrongylus vasorum (Reduction of the level of infection by immature adult (L5) and adult parasite stages; see specific treatment and prevention disease schedules under section “Administration routes and dosage”),

Crenosoma vulpis (Reduction of the level of infection).

Heartworm

Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against cestodes is indicated.

For cats it treats:

For cats with, or at risk from mixed infections of cestodes, gastrointestinal nematodes, and/or heartworm. This veterinary medicinal product is only indicated when use against cestodes and nematodes or prevention of heartworm disease is indicated at the same time.

Cestodes

Treatment of tapeworm:

Dipylidium caninum

Taenia spp.

Echinococcus multilocularis

Gastrointestinal nematodes

Treatment of: Hookworm: Ancylostoma tubaeforme

Roundworm: Toxocara cati

Heartworm

Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against cestodes is indicated.

How does Milbemax work?
It contains Milbemycin oxime and Praziquantel.

Milbemycin oxime belongs to the group of macrocyclic lactones, isolated from the fermentation of Streptomyces hygroscopicus var. aureolacrimosus. It is active against mites, against larval and adult stages of nematodes as well as against larvae of Dirofilaria immitis.

The activity of milbemycin is related to its action on invertebrate neurotransmission: Milbemycin oxime, like avermectins and other milbemycins, increases nematode and insect membrane permeability to chloride ions via glutamate-gated chloride ion channels (related to vertebrate GABAA and glycine receptors). This leads to hyperpolarisation of the neuromuscular membrane and flaccid paralysis and death of the parasite.

Praziquantel is an acylated pyrazino-isoquinoline derivative. Praziquantel is active against cestodes and trematodes. It modifies the permeability for calcium (influx of Ca2+) in the membranes of the parasite inducing an imbalance in the membrane structures, leading to membrane depolarisation and almost instantaneous contraction of the musculature (tetany), rapid vacuolization of the syncytial tegument and subsequent tegumental disintegration (blebbing), resulting in easier expulsion from the gastrointestinal tract or death of the parasite.

How should I administer Milbemax to my pet?
Orally, by mouth, with or after food. It is a tablet. Wash hands after use.

It is recommended to treat all the animals living in the same household concomitantly.

What is the correct dosage of Milbemax for my animal's weight and species?

The correct dose for your animal is as prescribed by your vet. Your vet will follow the data sheet for the medication prescribed and for some medications will adjust this taking into consideration your animal's medical history.

How long should I continue with Milbemax for?

You should continue for the length of time your vet prescribed the medication for. Please read the label your vet has attached to the medication. If you suspect that your pet may be having an adverse reaction to a medication, please contact your vet for advice on continuing the medication.

What should I do if I miss a dose of Milbemax?

If you miss a dose of medication, please contact your vet for advice on when to give the next dose.

Where can I buy Milbemax?

You can purchase Milbemax cheaper than from your Vet Practice from www.vets4u.uk. To contact vets4u.uk, call us on +44 116 218 4244 between 09:30am and 4:30pm Monday to Friday, chat to us directly or email us at mail@vets4u.uk.

Does Milbemax need a prescription?

Yes, as it is classified as a POM-V.

How can I buy Milbemax from Vets4u?

You can buy Milbemax via our website via a valid prescription by adding to the basket on our website www.vets4u.uk.

NOAH Compendium Datasheet Link to Milbemax

Milbemax Datasheet

What are the side-effects of Milbemax?
The cat product:
Very rare (<1 animal / 10,000 animals treated, including isolated reports).

Digestive tract disorders (such as Diarrhoea, Emesis) Hypersensitivity reaction Neurological disorders (such as Ataxia and Muscle tremor) Systemic disorders (such as Lethargy).

The dog product:
Very rare (<1 animal / 10 000 animals treated, including isolated reports).

Digestive tract disorders (such as Diarrhoea, Drooling, Emesis)

Hypersensitivity reaction.

Neurological disorders (such as Ataxia, Convulsions, Muscle tremors) Systemic disorders (such as Anorexia, Lethargy).

Reporting adverse events is important.

It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See also the package leaflet for contact details.

Does Milbemax cover lungworm?
Yes.

Does Milbemax treat lungworm?
Yes.

What is Milbemax for dogs?
It is a prescription medication for use in dogs and cats, containing the drugs Milbemycin Oxime and Praziquantel, used to treat a variety of parasitic worms.

Does Milbemax prevent lungworm?
Yes, if given every 4 weeks.

What does Milbemax cover?
It covers roundworms, tapeworms, lungworm (to prevent lungworm it must be given every 4 weeks, to treat it needs to be given weekly for 4 doses), heartworm, whipworm and hookworm.

Can you give Bravecto and Milbemax at the same time?

Bravecto has no known drug interaction stated in the datasheet and the datasheet for Milbemax does not state Bravecto as a contraindicated medication. If you have any questions on drug combinations for your specific pet, please speak to your vet.

Does Milbemax cover tapeworm?
Yes.

How long does Milbemax last?
It will target any parasites present on the day of administration. The frequency of administration should be discussed with your vet, as it depends on where you live and lifestyle factors of your pet, which influence their risk of being infected with the parasites.

How long does Milbemax take to work in dogs?
It depends on which worm you are treating. For lungworm treatment, as opposed to prevention, it needs to be given weekly for 4 weeks. It is rapidly absorbed into the blood stream and some other worms will be killed much sooner.

How often to use Milbemax for dogs?
For prevention of lungworm it can be used every 4 weeks.

Is Milbemax a good wormer?
It is licensed for use to treat roundworms, tapeworms, lungworm, heartworm, whipworm, and hookworm.

How much does Milbemax cost?
This varies, you can buy it from your vet or online, with a written prescription from your vet (which is chargeable). If you wish to check the price of purchasing it online, from a VMD registered online pharmacy, please contact us at www.vets4u.uk.

Is Milbemax safe for pregnant dogs?
It is licensed for use in pregnant and lactating bitches.

Can Milbemax be given together with other medications?
Speak to your veterinary surgeon regarding any drug combinations.

Can Milbemax cause diarrhoea?
In rare occasions, yes.

Can you crush Milbemax for cats?
Yes, it can be given with or after food.

Answers Compiled by our RCVS Registered Veterinary Surgeon.